Op-jpep160030 1033..1043
نویسندگان
چکیده
Objective Anxiety has both state/trait and cognitive/somatic dimensions, and these distinctions may be particularly relevant for children with medical problems. This two-part study adapted the State-Trait Inventory for Cognitive and Somatic Anxiety (STICSA) and confirmed its factor structure in a sample of children in a primary care clinic. Methods STICSA items were adapted for reading level and piloted in a small group of children. Next, 250 children (12.36 2.7 years) completed the adapted version, the STICSA-C. Results Separate confirmatory factor analyses conducted on the State and Trait forms of the STICSA-C confirmed the two-factor structure of the original measure (i.e., cognitive and somatic anxiety) and suggested an improved parsimonious model. Conclusions Support was found for use of the STICSA-C as a reasonably good internally consistent measure for assessing cognitive and somatic anxiety in pediatric samples. Further investigation of its reliability and validity with replication in pediatric populations is warranted.
منابع مشابه
The 10-cages and derived configurations
Symmetry properties of the three 10-cages on 70 vertices are investigated. Being bipartite, these graphs are Levi graphs of triangleand quadrangle-free (353) con!gurations. For each of these graphs a Hamilton cycle is given via the associated LCF notation. Furthermore, the automorphism groups of respective orders 80, 120, and 24 are computed. A special emphasis is given to the Balaban 10-cage, ...
متن کاملBoundary Feedback Control of Unstable Heat Equation with Space and Time Dependent Coefficient
In this paper, we study the control of the linear heat equation with a space and time dependent coefficient function by the Dirichlet and Neumann boundary control laws. This equation models the heat diffusion and space, time dependent heat generation in a one dimensional rod. Without control, the system is unstable if the coefficient function is positive and large. With boundary control based o...
متن کاملA phase I clinical and pharmacokinetic study of oral CI-1033 in combination with docetaxel in patients with advanced solid tumors.
PURPOSE CI-1033 is an orally available 4-anilinoquinazolone irreversible tyrosine kinase inhibitor of erbB-1, erbB-2, and erbB-4. We conducted a dose escalation study of CI-1033 with docetaxel to assess the safety profile and pharmacokinetics of the combination and to establish the maximum tolerated dose. EXPERIMENTAL DESIGN Twenty-six patients with advanced solid tumors were treated on four ...
متن کاملRadiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo.
PURPOSE Overexpression of the ErbB family of receptor tyrosine kinases has been associated with uncontrolled growth of many tumor types and, therefore, presents a promising molecular target for cancer therapy. CI-1033 is a small molecule tyrosine kinase inhibitor that differs from other 4-anilinoquinazolines by being a pan ErbB (instead of epidermal growth factor receptor-specific) irreversible...
متن کاملPhase 1 clinical and pharmacokinetics evaluation of oral CI-1033 in patients with refractory cancer.
PURPOSE To determine the tolerability and pharmacokinetics of oral CI-1033, a pan-erbB tyrosine kinase inhibitor, administered over 14 consecutive days of a 21-day cycle. DESIGN Phase 1, multicenter trial involving patients with solid tumors that are refractory to standard therapy. CI-1033 was administered initially at 300 mg/day to a minimum cohort of three patients. Dose escalation proceede...
متن کامل